"It was ordained at the beginning of the world that certain signs should prefigure certain events." (Marcus Tullius Cicero, "De Divinatione" ["Concerning Divination"], 44 BC)
"It would be a sign of great simplicity to think that the world was created in six days, or indeed at all in time; [...] Time is a thing posterior to the world. Therefore it would be correctly said that the world was not created in time, but that time had its existence in consequence of the world. For it is the motion of the heaven that has displayed the nature of time." (Philo Judaeus, "Allegories of the Sacred Laws" ["Legum allegoriae"], 1st century AD)
"All things are filled full of signs, and it is a wise man who can learn about one thing from another." (Plotinus, "Enneads", cca. 270 AD)
"We are meant to take them [the words ‘increase and multiply’] in a figurative sense. […] It is only in the case of signs outwardly given that we find increase and multiplication in the sense that a single truth can be expressed by several different means […] that a single expression can be interpreted in several different ways." (St. Augustine,"Confessions", 397- 400)
"Letters are signs of things, symbols of words, whose power is so great that without a voice they speak to us the words of the absent; for they introduce words by the eye, not by the ear." (Isidore of Seville, "Etymologiae", cca. 800-625)
"The Imagination that is raised in man (or any other creature imbued with the faculty of imagining) by words, or other voluntary signs, is that we generally call Understanding; and is common to Man and Beasts." (Thomas Hobbes, "Leviathan: Or, The Matter, Forme, & Power of a Common-wealth Ecclesiasticall and Civill", 1651)
"The signs of science are, some certain and infallible; some, uncertain. Certain, when he that pretendeth the science of anything, can teach the same; that is to say, demonstrate the truth thereof perspicuously to another; uncertain, when only some particular events answer to his pretence, and upon many occasions prove so as he says they must. " (Thomas Hobbes, "Leviathan: Or, The Matter, Forme, & Power of a Common-wealth Ecclesiasticall and Civill", 1651)
"It is obvious that if we could find characters or signs suited for expressing all our thoughts as clearly and as exactly as arithmetic expresses numbers or geometry expresses lines, we could do in all matters, insofar as they are subject to reasoning, all that we can do in arithmetic and geometry." (Gottfried W Leibniz, 1677)
"In signs, one sees an advantage for discovery that is greatest when they express the exact nature of a thing briefly and, as it were, picture it; then indeed, the labor of thought is wonderfully diminished” (Gottfried W Leibniz, [letter to Tschirnhaus] cca. 1686)
"As arithmetic and algebra are sciences of great clearness, certainty, and extent, which are immediately conversant about signs, upon the skillful use whereof they entirely depend, so a little attention to them may possibly help us to judge of the progress of the mind in other sciences, which, though differing in nature, design, and object, may yet agree in the general methods of proof and inquiry." (George Berkeley, "Alciphron: or the Minute Philosopher", 1732)
"[…] the sciences that are expressed by numbers or by other small signs, are easily learned; and without doubt this facility rather than its demonstrability is what has made the fortune of algebra." (Julien Offray de La Mettrie,"Man a Machine", 1747)
"Algebra is a general Method of Computation by certain Signs and Symbols which have been contrived for this Purpose, and found convenient. It is called an Universal Arithmetic, and proceeds by Operations and Rules similar to those in Common Arithmetic, founded upon the same Principles." (Colin Maclaurin,"A Treatise on Algebra", 1748)
"All abstract sciences are nothing but the study of relations between signs." (Denis Diderot, "Lettre sur les sourds et muets" ["Letter on the Deaf and Dumb"], 1751)