"He is not a true man of science who does not bring some sympathy to his studies, and expect to learn something by behavior as well as by application. It is childish to rest in the discovery of mere coincidences, or of partial and extraneous laws. The study of geometry is a petty and idle exercise of the mind if it is applied to no larger system than the starry one." (Henry D Thoreau, "A Week on the Concord and Merrimack Rivers", 1849)
"At the final stage you teach me that this wondrous and multicolored universe can be reduced to the atom and that the atom itself can be reduced to the electron. All this is good and I wait for you to continue. But you tell me of an invisible planetary system in which electrons gravitate around a nucleus. You explain this world to me with an image. I realize then that you have been reduced to poetry: I shall never know. Have I the time to become indignant? You have already changed theories. So that science that was to teach me everything ends up in a hypothesis, that lucidity founders in metaphor, that uncertainty is resolved in a work of art." (Albert Camus, "The Myth of Sisyphus", 1942)
"[…] anybody with a genuine system of prediction would be using it, not selling it." (Philip K Dick, "Solar Lottery", 1955)
"Science fiction is, very strictly and literally, analogous to science facts. It is a convenient analog system for thinking about new scientific, social, and economic ideas - and for re-examining old ideas." (John W Campbell Jr., "Prologue to Analog", 1962)
"A system has order, flowing from point to point. If something dams that flow, order collapses. The untrained might miss that collapse until it was too late. That's why the highest function of ecology is the understanding of consequences." (Frank Herbert, "Dune", 1965)
"Beyond a critical point within a finite space, freedom diminishes as numbers increase. This is as true of humans as it is of gas molecules in a sealed flask. The human question is not how many can possibly survive within the system, but what kind of existence is possible for those who do survive." (Frank Herbert, "Dune", 1965)
"Science offers a sounder basis on which to formulate systems of thought and ethics." (Michael Moorcock, "Behold the Man", 1967)
"Deception, in a system of this sort, can be defined simply as entropy [...] And of course, entropy, or degradation of order, is avoided by all civilized beings, since no local increase in complexity can offset entropic effects in the larger matrix." (James Tiptree Jr, "Faithful to Thee, Terra, in Our Fashion" ["Parimutuel Planet"], Galaxy, 1969)
"To the paranoid, nothing is a surprise; everything happens exactly as he expected, and sometimes even more so. It all fits into his system. For us, though, there can be no system; maybe all systems - that is, any theoretical, verbal, symbolic, semantic, etc. formulation that attempts to act as an all-encompassing, all-explaining hypothesis of what the universe is about - are manifestations of paranoia. We should be content with the mysterious, the meaningless, the contradictory, the hostile, and most of all the unexplainably warm and giving." (Philip K Dick, "The Android and the Human", [speech] 1972)
"Thought is a matrix which engenders its own reality. The ideas, concepts, belief-systems that your ancestors trapped have become your trap." (Alfred A Attanasio, "Radix", 1981)
"Dangers lurk in all systems. Systems incorporate the unexamined beliefs of their creators. Adopt a system, accept its beliefs, and you help strengthen the resistance to change." (Frank Herbert, "God Emperor of Dune", 1984)
"Living systems are never in equilibrium. They are inherently unstable. They may seem stable, but they’re not. Everything is moving and changing. In a sense, everything is on the edge of collapse. (Michael Crichton, "Jurassic Park", 1990)
"The system of life on this planet is so astoundingly complex that it was a long time before man even realized that it was a system at all and that it wasn't something that was just there." (Douglas N Adams, "Last Chance to See", 1990)
"It is a concatenation of synergistic interactions; the whole system is on the period-doubling route to Chaos! [...] in layman’s terms, it means that everything gets twice as bad, twice as fast, until everything falls completely apart!" (William Gibson & Bruce Sterling, "The Difference Engine", 1991)
"Any information system of sufficient complexity will inevitably become infected with viruses - viruses generated from within itself." (Neal Stephenson, "Snow Crash", 1992)
"The thing the ecologically illiterate don't realize about an ecosystem is that it's a system. A system! A system maintains a certain fluid stability that can be destroyed by a misstep in just one niche." (Frank Herbert, "Dune: House Atreides", 1999)