"[…] to the unpreoccupied mind, complex numbers are far from natural or simple and they cannot be suggested by physical observations. Furthermore, the use of complex numbers is in this case not a calculational trick of applied mathematics but comes close to being a necessity in the formulation of quantum mechanics." (Eugene Wigner,"The Unreasonable Effectiveness of Mathematics in the Natural Sciences", 1960)
"[...] sciences do not try to explain, they hardly even try to interpret, they mainly make models. By a model is meant a mathematical construct which, with the addition of certain verbal interpretations, describes observed phenomena. The justification of such a mathematical construct is solely and precisely that it is expected to work - that is, correctly to describe phenomena from a reasonably wide area. Furthermore, it must satisfy certain aesthetic criteria - that is, in relation to how much it describes, it must be rather simple." (John von Neumann, Method in the physical sciences", 1961)
"[...] thermodynamics knows of no such notion as the 'entropy of a physical system'. Thermodynamics does have the concept of the entropy of a thermodynamic system; but a given physical system corresponds to many different thermodynamic systems." (Edwin T Jaynes, "Gibbs vs Boltzmann Entropies", 1964)
"As mechanics is the science of motions and forces, so thermodynamics is the science of forces and entropy. What is entropy? Heads have split for a century trying to define entropy in terms of other things. Entropy, like force, is an undefined object, and if you try to define it, you will suffer the same fate as the force definers of the seventeenth and eighteenth centuries: Either you will get something too special or you will run around in a circle." (Clifford Truesdell, "Six Lectures on Modern Natural Philosophy", 1966)
"Despite two centuries of study, the integrals of general dynamical systems remain covered with darkness. To save the classical thermostatics, the practical success of which is shown by the wide use to which it has been put, we must find a way out. That is, we must find some mathematical connection between time averages of the functions of physical interest and the corresponding simple canonical averages." (Clifford Truesdell, "Six Lectures on Modern Natural Philosophy", 1966)
"The mere fact that the same mathematical expression -Σ pi log(pi) [i is index], occurs both in statistical mechanics and in information theory does not in itself establish any connection between these fields. This can be done only by finding new viewpoints from which thermodynamic entropy and information-theory entropy appear as the same concept." (Edwin T Jaynes, "Information Theory and Statistical Mechanics" I, 1956)
"Thermostatics, which even now is usually called thermodynamics, has an unfortunate history and a cancerous tradition. It arose in a chaos of metaphysical and indeed irrational controversy, the traces of which drip their poison even today. As compared with the older science of mechanics and the younger science of electromagnetism, its mathematical structure is meager. Though claims for its breadth of application are often extravagant, the examples from which its principles usually are inferred are most special, and extensive mathematical developments based on fundamental equations, such as typify mechanics and electromagnetism, are wanting. The logical standards acceptable in thermostatics fail to meet the criteria of other exact sciences [...]." (Clifford Truesdell, "Six Lectures on Modern Natural Philosophy", 1966)
"Conventional physics deals only with closed systems, i.e. systems which are considered to be isolated from their environment. [...] However, we find systems which by their very nature and definition are not closed systems. Every living organism is essentially an open system. It maintains itself in a continuous inflow and outflow, a building up and breaking down of components, never being, so long as it is alive, in a state of chemical and thermodynamic equilibrium but maintained in a so-called steady state which is distinct from the latter." (Ludwig von Bertalanffy, "General System Theory", 1968)
"It is possible to know thermodynamics without understanding it." (Richard E Dickerson, "Molecular Thermodynamics", 1969)
"My analysis of living systems uses concepts of thermodynamics, information theory, cybernetics, and systems engineering, as well as the classical concepts appropriate to each level. The purpose is to produce a description of living structure and process in terms of input and output, flows through systems, steady states, and feedbacks, which will clarify and unify the facts of life." (James G Miller, "Living Systems: Basic Concepts", 1969)
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