"The solution of the difficulty is that the two mental pictures which experiment lead us to form - the one of the particles, the other of the waves - are both incomplete and have only the validity of analogies which are accurate only in limiting cases." (Werner Heisenberg,"On Quantum Mechanics", 1930)
"The truly scientific mind is altogether unafraid of the new, and while having no mercy for ideas which have served their turn or shown their uselessness, it will not grudge to any unfamiliar conception its moment of full and friendly attention, hoping to expand rather than to minimize what small core of usefulness it may happen to contain." (Wilfred Trotter, "Observation and Experiment and Their Use in the Medical Sciences", British Medical Journal Vol. 2, 1930)
"When an observation is made on any atomic system that has been prepared in a given way and is thus in a given state, the result will not in general be determinate, i.e. if the experiment is repeated several times under identical conditions several different results may be obtained. If the experiment is repeated a large number of times it will be found that each particular result will be obtained a definite fraction of the total number of times, so that one can say there is a definite probability of its being obtained any time that the experiment is performed. This probability the theory enables one to calculate." (Paul A M Dirac, "The Principles of Quantum Mechanics ", 1930)
"Every sentence in order to have definite scientific meaning must be practically or at least theoretically verifiable as either true or false upon the basis of experimental measurements either practically or theoretically obtainable by carrying out a definite and previously specified operation in the future. The meaning of such a sentence is the method of its verification." (Walter A Shewhart, "Economic Control of Quality of Manufactured Product", 1931)
"The distinguishing feature of modern scientific thought lies in the fact that it begins by discarding all a priori conceptions about the nature of reality - or about the ultimate nature of the universe - such as had characterized practically all Greek philosophy and all medieval thinking as well, and takes instead, as its starting point, well-authenticated, carefully tested experimental facts, no matter whether these facts seen at the moment to fit into any general philosophical scheme or not - that is, no matter whether they seem at the moment to be reasonable or not." (Robert A Millikan, "Professor Einstein at the California Institute of Technology", Science Vol. 73 (1893), 1931)
"'Schema' refers to an active organisation of past reactions, or of past experiences, which must always be supposed to be operating in any well-adapted organic response. That is, whenever there is any order or regularity of behavior, a particular response is possible only because it is related to other similar responses which have been serially organised, yet which operate, not simply as individual members coming one after another, but as a unitary mass. Determination by schemata is the most fundamental of all the ways in which we can be influenced by reactions and experiences which occurred some time in the past. All incoming impulses of a certain kind, or mode, go together to build up an active, organised setting: visual, auditory, various types of cutaneous impulses and the like, at a relatively low level; all the experiences connected by a common interest: in sport, in literature, history, art, science, philosophy, and so on, on a higher level." (Frederic C Bartlett, "Remembering: A study in experimental and social psychology", 1932)
"In every important advance the physicist finds that the fundamental laws are simplified more and more as experimental research advances. He is astonished to notice how sublime order emerges from what appeared to be chaos. And this cannot be traced back to the workings of his own mind but is due to a quality that is inherent in the world of perception." (Albert Einstein, 1932)
"The discoveries in physical science, the triumphs in invention, attest the value of the process of trial and error. In large measure, these advances have been due to experimentation." (Louis Brandeis, "Judicial opinions", 1932)
"The sequence of different positions of the same particle at different times forms a one-dimensional continuum in the four-dimensional space-time, which is called the world-line of the particle. All that physical experiments or observations can teach us refers to intersections of world-lines of different material particles, light-pulsations, etc., and how the course of the world-line is between these points of intersection is entirely irrelevant and outside the domain of physics. The system of intersecting world-lines can thus be twisted about at will, so long as no points of intersection are destroyed or created, and their order is not changed. It follows that the equations expressing the physical laws must be invariant for arbitrary transformations." (Willem de Sitter, "Kosmos", 1932)
"Thinking is an experimental dealing with small quantities of energy, just as a general moves miniature figures over a map before setting his troops in action." (Sigmund Freud, "New Introductory Lectures on Psychoanalysis", 1932)
"In every experiment on living organisms, there must remain an uncertainty as regards the physical conditions to which they are subjected, and the idea suggests itself that the minimal freedom we must allow the organism in this respect is just large enough to permit it, so to say, to hide its ultimate secrets from us." (Niels H D Bohr, "Light and Life", Nature Vol. 131 (3309), 1933)
"A scientist, whether theorist or experimenter, puts forward statements, or systems of statements, and tests them step by step. In the field of the empirical sciences, more particularly, he constructs hypotheses, or systems of theories, and tests them against experience by observation and experiment." (Karl Popper, "The Logic of Scientific Discovery", 1934)
"Science is a system of statements based on direct experience, and controlled by experimental verification. Verification in science is not, however, of single statements but of the entire system or a sub-system of such statements." (Rudolf Carnap, "The Unity of Science", 1934)
"Today's scientists have substituted mathematics for experiments, and they wander off through equation after equation, and eventually build a structure which has no relation to reality." (Nikola Tesla, "Radio Power Will Revolutionize the World", Modern Mechanics and Inventions, 1934)
"While it is true that theory often sets difficult, if not impossible tasks for the experiment, it does, on the other hand, often lighten the work of the experimenter by disclosing cogent relationships which make possible the indirect determination of inaccessible quantities and thus render difficult measurements unnecessary." (Georg Joos, "Theoretical Physics", 1934)
"In experimental science facts of the greatest importance are rarely discovered accidentally: more frequently new ideas point the way towards them." (Erwin Schrödinger, "Science and the Human Temperament", 1935)
"In relation to any experiment we may speak of this hypothesis as the null hypothesis, and it should be noted that the null hypothesis is never proved or established, but is possibly disproved, in the course of experimentation. Every experiment may be said to exist only in order to give the facts a chance of disproving the null hypothesis." (Ronald Fisher, "The Design of Experiments", 1935)
"Mathematics alone make us feel the limits of our intelligence. For we can always suppose in the case of an experiment that it is inexplicable because we don’t happen to have all the data. In mathematics we have all the data [...] and yet we don’t understand. We always come back to the contemplation of our human wretchedness. What force is in relation to our will, the impenetrable opacity of mathematics is in relation to our intelligence." (Simone Weil, "The Notebooks of Simone Weil" Vol. 2, 1935)
"When an induction, based on observations, is made, it is not intended that it shall be accepted as a universal truth, but it is advanced as a hypothesis for further study. Additional observations are then made and the results compared with the results expected from the hypothesis. If there is more deviation between the experimental results and the computed results than can be expected from the inaccuracies of observation and measurement, the scientist discards the' hypothesis and tries to formulate another."
"Statistics is a scientific discipline concerned with collection, analysis, and interpretation of data obtained from observation or experiment. The subject has a coherent structure based on the theory of Probability and includes many different procedures which contribute to research and development throughout the whole of Science and Technology." (Egon Pearson, 1936)
"[T]he sudden inventions characteristic of the sixth stage [of infant development] are in reality the product of a long evolution of schemata and not only of an internal maturation of perceptive structures. [..] This is revealed by the existence of a fifth stage, characterized by experimental groping. […] What does this mean if not that the practice of actual experience is necessary in order to acquire the practice of mental experience and that invention does not arise entirely preformed despite appearances?" (Jean Piaget, The origin of intelligence in children" 1936)
"It is wholly absurd to maintain that an intellectual experiment is important only in proportion as it can be checked by measurement; for if this were so, there could be no exact geometrical proof. A line drawn on paper is not really a line but a more or less narrow strip, and a point a larger or smaller spot." (Max Planck, "The Philosophy of Physics", 1936)
"[...] great as may be the potency of this [the experimental method], or of the preceding methods, there is yet another one so vital that, if lacking it, any study is thought by many authorities not to be scientific in the full sense of the word. This further and crucial method is that of measurement [...]" (Charles Spearman, "Psychology Down the Ages" Vol. 1, 1937)
"At the beginning of its existence as a science, biology was forced to take cognizance of the seemingly boundless variety of living things, for no exact study of life phenomena was possible until the apparent chaos of the distinct kinds of organisms had been reduced to a rational system. Systematics and morphology, two predominantly descriptive and observational disciplines, took precedence among biological sciences during the eighteenth and nineteenth centuries. More recently physiology has come to the foreground, accompanied by the introduction of quantitative methods and by a shift from the observationalism of the past to a predominance of experimentation." (Theodosius Dobzhansky, "Genetics and the Origin of Species", 1937)
"Modem physics is, indeed, not unlike a ship, drawing nearer to a goal not yet in sight, but so tossed about by the buffetings of experiment and working hypothesis that the passenger scarcely knows whether he is progressing or drifting." (Herbert Dingle, "Through Science to Philosophy", 1937)
"The formulation of a problem is often more essential than its solution, which may be merely a matter of mathematical or experimental skill. To raise new questions, new possibilities, to regard old problems from a new angle requires creative imagination and marks real advances in science." (Albert Einstein & Leopold Infeld, "The Evolution of Physics", 1938)
"The laws of science are the permanent contributions to knowledge - the individual pieces that are fitted together in an attempt to form a picture of the physical universe in action. As the pieces fall into place, we often catch glimpses of emerging patterns, called theories; they set us searching for the missing pieces that will fill in the gaps and complete the patterns. These theories, these provisional interpretations of the data in hand, are mere working hypotheses, and they are treated with scant respect until they can be tested by new pieces of the puzzle." (Edwin P Whipple, "Experiment and Experience", [Commencement Address, California Institute of Technology] 1938)
"To consult the statistician after an experiment is finished is often merely to ask him to conduct a post mortem examination. He can perhaps say what the experiment died of." (Sir Ronald A Fisher, [presidential address] 1938)
"An inference, if it is to have scientific value, must constitute a prediction concerning future data. If the inference is to be made purely with the help of the distribution theory of statistics, the experiments that constitute evidence for the inference must arise from a state of statistical control; until that state is reached, there is no universe, normal or otherwise, and the statistician’s calculations by themselves are an illusion if not a delusion. The fact is that when distribution theory is not applicable for lack of control, any inference, statistical or otherwise, is little better than a conjecture. The state of statistical control is therefore the goal of all experimentation." (William E Deming, "Statistical Method from the Viewpoint of Quality Control", 1939)
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