On Experiments (1860-1869)

"Experimental facts alone cannot satisfy the mind: we desire to know the cause of the fact; we search after the principle by the operation of which the phenomena are produced." (John Tyndall, "Heat: A Mode of Motion", 1863)

"A theory is merely a scientific idea controlled by experiment." (Claude Bernard, "An Introduction to the Study of Experimental Medicine", 1865)

"Experiment is fundamentally only induced observation." (Claude Bernard, "An Introduction to the Study of Experimental Medicine", 1865)

"Observation is a passive science, experimentation an active science." (Claude Bernard, "An Introduction to the Study of Experimental Medicine", 1865)

"An anticipative idea or an hypothesis is, then, the necessary starting point for all experimental reasoning." (Claude Bernard, "An Introduction to the Study of Experimental Medicine", 1865)

"An anticipative idea or an hypothesis is, then, the necessary starting point for all experimental reasoning. Without it, we could not make any investigation at all nor learn anything; we could only pile up sterile observations. If we experiment without a preconceived idea, we should move at random […]" (Claude Bernard, "An Introduction to the Study of Experimental Medicine", 1865)

"Considered by itself, the experimental method is nothing but reasoning by whose help we methodically submit our ideas to experience, - the experience of facts." (Claude Bernard, "An Introduction to the Study of Experimental Medicine", 1865)

"Observation is a passive science, experimentation an active science." (Claude Bernard, "An Introduction to the Study of Experimental Medicine", 1865)

"Speaking concretely, when we say ‘making experiments or making observations’, we mean that we devote ourselves to investigation and to research, that we make attempts and trials in order to gain facts from which the mind, through reasoning, may draw knowledge or instruction.  Speaking in the abstract, when we say, ‘relying on observation and gaining experience’, we mean that observation is the mind’s support in reasoning, and experience the mind’s support in deciding, or still better, the fruit of exact reasoning applied to the interpretation of facts. Observation, then, is what shows facts; experiment is what teaches about facts and gives experience in relation to anything." (Claude Bernard, "An Introduction to the Study of Experimental Medicine", 1865)

"Any opinion as to the form in which the energy of gravitation exists in space is of great importance, and whoever can make his opinion probable will have, made an enormous stride in physical speculation. The apparent universality of gravitation, and the equality of its effects on matter of all kinds are most remarkable facts, hitherto without exception; but they are purely experimental facts, liable to be corrected by a single observed exception. We cannot conceive of matter with negative inertia or mass; but we see no way of accounting for the proportionality of gravitation to mass by any legitimate method of demonstration. If we can see the tails of comets fly off in the direction opposed to the sun with an accelerated velocity, and if we believe these tails to be matter and not optical illusions or mere tracks of vibrating disturbance, then we must admit a force in that direction, and we may establish that it is caused by the sun if it always depends upon his position and distance." (James C Maxwell, [Letter to William Huggins] 1868)

"Isolated facts and experiments have in themselves no value, however great their number may be. They only become valuable in a theoretical or practical point of view when they make us acquainted with the law of a series of uniformly recurring phenomena, or, it may be, only give a negative result showing an incompleteness in our knowledge of such a law, till then held to be perfect." (Hermann von Helmholtz, "The Aim and Progress of Physical Science", 1869)