"A scientist who is no longer capable of framing a hypothesis - or never was - is not a scientist but a methodological fossil." (Alexander Goldenweiser, "Robots or Gods", 1931)
"Abstraction is the detection of a common quality in the characteristics of a number of diverse observations […] A hypothesis serves the same purpose, but in a different way. It relates apparently diverse experiences, not by directly detecting a common quality in the experiences themselves, but by inventing a fictitious substance or process or idea, in terms of which the experience can be expressed. A hypothesis, in brief, correlates observations by adding something to them, while abstraction achieves the same end by subtracting something." (Herbert Dingle, Science and Human Experience, 1931)
"If we consistently act on the optimistic hypothesis, this hypothesis will tend to be realised; whilst by acting on the pessimistic hypothesis we can keep ourselves for ever in the pit of want." (John M Keynes, "Essays in Persuasion", 1931)
"Scientific hypotheses are intuitive leaps in the dark." (Alexander Goldenweiser, "Robots or Gods: An Essay on Craft and Mind", American Journal of Sociology 37 (3), 1931)
"A Weltanschauung [worldview] is an intellectual construction which solves all the problems of our existence uniformly on the basis of one overriding hypothesis, which, accordingly, leaves no question unanswered and in which everything that interests us finds its fixed place [...] the worldview of science already departs noticeably from our definition. It is true that it too assumes the uniformity of the explanation of the universe; but it does so only as a programme, the fulfillment of which is relegated to the future." Sigmund Freud, "New introductory lectures on psycho-analysis", 1932)
"Every hypothesis in physical science has to go through a period of difficult gestation and parturition before it can be brought out into the light of day and handed to others, ready-made in scientific form so that it will be, as it were, fool-proof in the hands of outsiders who wish to apply it." (Max Planck, "Where Is Science Going?", 1932)
"If an explanation is so vague in its inherent nature, or so unskillfully molded in its formulation, that specific deductions subject to empirical verification or refutation can not be based upon it, then it can never serve as a working hypothesis. A hypothesis with which one can not work is not a working hypothesis." (Douglas W Johnson, "Role of Analysis in Scientific Investigation", Bulletin of the Geological Society of America, 1933)
"A scientist, whether theorist or experimenter, puts forward statements, or systems of statements, and tests them step by step. In the field of the empirical sciences, more particularly, he constructs hypotheses, or systems of theories, and tests them against experience by observation and experiment." (Karl Popper, "The Logic of Scientific Discovery", 1934)
"I think that we shall have to get accustomed to the idea that we must not look upon science as a 'body of knowledge,' but rather as a system of hypotheses; that is to say, as a system of guesses or anticipations which in principle cannot be justified, but with which we work as long as they stand up to tests, and of which we are never justified in saying that we know they are 'true' or 'more or less certain' or even 'probable’." (Karl R Popper, "The Logic of Scientific Discovery", 1934)
"Science does not aim, primarily, at high probabilities. It aims at a high informative content, well backed by experience. But a hypothesis may be very probable simply because it tells us nothing, or very little." (Karl Popper, "The Logic of Scientific Discovery", 1934)
"All the theories and hypotheses of empirical science share this provisional character of being established and accepted ‘until further notice’, whereas a mathematical theorem, once proved, is established once and for all; it holds with that particular certainty which no subsequent empirical discoveries, however unexpected and extraordinary, can ever affect to the slightest extent." (Carl G Hempel, "Geometry and Empirical Science", 1935)
"In relation to any experiment we may speak of this hypothesis as the null hypothesis, and it should be noted that the null hypothesis is never proved or established, but is possibly disproved, in the course of experimentation. Every experiment may be said to exist only in order to give the facts a chance of disproving the null hypothesis." (Ronald Fisher, "The Design of Experiments", 1935)
"When an induction, based on observations, is made, it is not intended that it shall be accepted as a universal truth, but it is advanced as a hypothesis for further study. Additional observations are then made and the results compared with the results expected from the hypothesis. If there is more deviation between the experimental results and the computed results than can be expected from the inaccuracies of observation and measurement, the scientist discards the' hypothesis and tries to formulate another."
"[…] in the world of immediate experience, the world of things is there. Trees grow, day follows night, and death supervenes upon life. One may not say that relations here are external or even internal. They are not relations at all. They are lost in the indiscreptibility of things and events, which are what they are. The world which is the test of all observations and all scientific hypothetical reconstruction has in itself no system that can be isolated as a structure of laws, or uniformities, though all laws and formulations of uniformities must be brought to its court for its imprimatur." (George H Mead, "The Philosophy of the Act", 1938)
"The laws of science are the permanent contributions to knowledge - the individual pieces that are fitted together in an attempt to form a picture of the physical universe in action. As the pieces fall into place, we often catch glimpses of emerging patterns, called theories; they set us searching for the missing pieces that will fill in the gaps and complete the patterns. These theories, these provisional interpretations of the data in hand, are mere working hypotheses, and they are treated with scant respect until they can be tested by new pieces of the puzzle." (Edwin P Whipple, "Experiment and Experience", [Commencement Address, California Institute of Technology] 1938)
"One can live in a prefabricated world, smugly and without question, or one can indulge perhaps the greatest human excitement: that of observation to speculation to hypothesis. This is a creative process, probably the highest and most satisfactory we know." (Edward F Ricketts et al, "Between Pacific Tides", 1939)
"What the use of P [the significance level] implies, therefore, is that a hypothesis that may be true may be rejected because it has not predicted observable results that have not occurred." (Harold Jeffreys, "Theory of Probability", 1939)
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