"The final truth about phenomena resides in the mathematical description of it; so long as there is no imperfection in this, our knowledge is complete. We go beyond the mathematical formula at our own risk; we may find a [nonmathematical] model or picture that helps us to understand it, but we have no right to expect this, and our failure to find such a model or picture need not indicate that either our reasoning or our knowledge is at fault." (James Jeans, "The Mysterious Universe", 1930)
"Scientific discovery and scientific knowledge have been achieved only by those who have gone in pursuit of them without any practical purpose whatsoever in view." (Max Planck, "Where is Science Going?", 1932)
"As facts and knowledge accumulate, the claim of the scientist to an understanding of the world in a certain sense diminishes." (Werner K Heisenberg, "Zur Geschichte der physikalischen Naturerklärung", 1933)
"The urge to knowledge is so deeply rooted in man that it can scarcely be omitted from a list of life's important needs." (Hans Reichenbach, "Atom and Cosmos: The World of Modern Physics", 1933)
"Maximal knowledge of a total system does not necessarily include total knowledge of all its parts, not even when these are fully separated from each other and at the moment are not influencing each other at all. Thus it may be that some part of what one knows may pertain to relations […] between the two subsystems (we shall limit ourselves to two), as follows: if a particular measurement on the first system yields this result, then for a particular measurement on the second the valid expectation statistics are such and such; but if the measurement in question on the first system should have that result, then some other expectation holds for that one the second. […] In this way, any measurement process at all or, what amounts to the same, any variable at all of the second system can be tied to the not-yet-known value of any variable at all of the first, and of course vice versa also." (Erwin Schrödinger, "The Present Situation in Quantum Mechanics", 1935)
"The laws of science are the permanent contributions to knowledge - the individual pieces that are fitted together in an attempt to form a picture of the physical universe in action. As the pieces fall into place, we often catch glimpses of emerging patterns, called theories; they set us searching for the missing pieces that will fill in the gaps and complete the patterns. These theories, these provisional interpretations of the data in hand, are mere working hypotheses, and they are treated with scant respect until they can be tested by new pieces of the puzzle." (Edwin P Whipple, "Experiment and Experience", [Commencement Address, California Institute of Technology] 1938)
"We have discovered that it is actually an aid in the search for knowledge to understand the nature of the knowledge we seek." (Arthur S Eddington, "The Philosophy of Physical Science", 1938)
"[…] reality is a system, completely ordered and fully intelligible, with which thought in its advance is more and more identifying itself. We may look at the growth of knowledge […] as an attempt by our mind to return to union with things as they are in their ordered wholeness. […] and if we take this view, our notion of truth is marked out for us. Truth is the approximation of thought to reality […] Its measure is the distance thought has travelled […] toward that intelligible system […] The degree of truth of a particular proposition is to be judged in the first instance by its coherence with experience as a whole, ultimately by its coherence with that further whole, all comprehensive and fully articulated, in which thought can come to rest." (Brand Blanshard, "The Nature of Thought" Vol. II, 1939)
"The failure of the social sciences to think through and to integrate their several responsibilities for the common problem of relating the analysis of parts to the analysis of the whole constitutes one of the major lags crippling their utility as human tools of knowledge." (Robert S Lynd, "Knowledge of What?", 1939)
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