"Inductive inference is the only process known to us by which essential new knowledge comes into the world." (Sir Ronald A Fisher, "The Design of Experiments", 1971)
"A discovery must be, by definition, at variance with existing knowledge." (Albert Szent-Gyorgyi, "Dionysians and Apollonians", Science 176, 1972)
"Nature is a network of happenings that do not unroll like a red carpet into time, but are intertwined between every part of the world; and we are among those parts. In this nexus, we cannot reach certainty because it is not there to be reached; it goes with the wrong model, and the certain answers ironically are the wrong answers. Certainty is a demand that is made by philosophers who contemplate the world from outside; and scientific knowledge is knowledge for action, not contemplation. There is no God’s eye view of nature, in relativity, or in any science: only a man’s eye view." (Jacob Bronowski, "The Identity of Man", 1972)
"The human condition can almost be summed up in the observation that, whereas all experiences are of the past, all decisions are about the future. It is the great task of human knowledge to bridge this gap and to find those patterns in the past which can be projected into the future as realistic images." (Kenneth E Boulding, [foreword] 1972)
"Human knowledge is personal and responsible, an unending adventure at the edge of uncertainty." (Jacob Bronowski, "The Ascent of Man", 1973)
"In moving from conjecture to experimental data, (D), experiments must be designed which make best use of the experimenter's current state of knowledge and which best illuminate his conjecture. In moving from data to modified conjecture, (A), data must be analyzed so as to accurately present information in a manner which is readily understood by the experimenter." (George E P Box & George C Tjao, "Bayesian Inference in Statistical Analysis", 1973)
"Discoveries are made by pursuing possibilities suggested by existing knowledge." (Michael Polanyi, "Meaning", 1975)
"Knowledge is not a series of self-consistent theories that converges toward an ideal view; it is rather an ever increasing ocean of mutually incompatible (and perhaps even incommensurable) alternatives, each single theory, each fairy tale, each myth that is part of the collection forcing the others into greater articulation and all of them contributing, via this process of competition, to the development of our consciousness." (Paul K Feyerabend, "Against Method: Outline of an Anarchistic Theory of Knowledge", 1975)
"Every judgment teeters on the brink of error. To claim absolute knowledge is to become monstrous. Knowledge is an unending adventure at the edge of uncertainty." (Frank Herbert, "Children of Dune", 1976)
"Owing to his lack of knowledge, the ordinary man cannot attempt to resolve conflicting theories of conflicting advice into a single organized structure. He is likely to assume the information available to him is on the order of what we might think of as a few pieces of an enormous jigsaw puzzle. If a given piece fails to fit, it is not because it is fraudulent; more likely the contradictions and inconsistencies within his information are due to his lack of understanding and to the fact that he possesses only a few pieces of the puzzle. Differing statements about the nature of things […] are to be collected eagerly and be made a part of the individual's collection of puzzle pieces. Ultimately, after many lifetimes, the pieces will fit together and the individual will attain clear and certain knowledge." (Alan R Beals, "Strategies of Resort to Curers in South India" [contributed in Charles M. Leslie (ed.), "Asian Medical Systems: A Comparative Study", 1976])
"Concepts form the basis for any science. These are ideas, usually somewhat vague (especially when first encountered), which often defy really adequate definition. The meaning of a new concept can seldom be grasped from reading a one-paragraph discussion. There must be time to become accustomed to the concept, to investigate it with prior knowledge, and to associate it with personal experience. Inability to work with details of a new subject can often be traced to inadequate understanding of its basic concepts." (William C Reynolds & Harry C Perkins, "Engineering Thermodynamics", 1977)
"Because of mathematical indeterminancy and the uncertainty principle, it may be a law of nature that no nervous system is capable of acquiring enough knowledge to significantly predict the future of any other intelligent system in detail. Nor can intelligent minds gain enough self-knowledge to know their own future, capture fate, and in this sense eliminate free will." (Edward O Wilson, "On Human Nature", 1978)
"Certainty, simplicity, vividness originate in popular knowledge. That is where the expert obtains his faith in this triad as the ideal of knowledge. Therein lies the general epistemological significance of popular science." (Ludwik Fleck, "Genesis and Development of a Scientific Fact", 1979)
"It is hard for us today to assimilate all the new ideas that are being suggested in response to the new information we have. We must remember that our picture of the universe is based not only on our scientific knowledge but also on our culture and our philosophy. What new discoveries lie ahead no one can say. There may well be civilizations in other parts of our galaxy or in other galaxies that have already accomplished much of what lies ahead for mankind. Others may just be beginning. The universe clearly presents an unending challenge." (Necia H Apfel & J Allen Hynek, "Architecture of the Universe", 1979)
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