"The dimmed outlines of phenomenal things all merge into one another unless we put on the focusing-glass of theory, and screw it up sometimes to one pitch of definition and sometimes to another, so as to see down into different depths through the great millstone of the world." (James C Maxwell, "Are There Real Analogies in Nature?", 1856)
"The method of scientific investigation is nothing but the expression of the necessary mode of working of the human mind. (Thomas H Huxley, "Our Knowledge of the Causes of the Phenomena of Organic Nature", 1863)
"Only within very narrow boundaries can man observe the phenomena which surround him; most of them naturally escape his senses, and mere observation is not enough." (Claude Bernard, "An Introduction to the Study of Experimental Medicine", 1865)
"[…] without the theory of evolution all the big general series of phenomena of organic nature remain completely incomprehensible and inexplicable riddles, while by means of this theory they can be explained simply and consistently. This holds especially true for two complexes of biological phenomena which we now in conclusion wish to single out in a few words. These form the subject of two special branches of physiology which so far have been largely neglected, namely, the ecology and chorology of organisms." (Ernst Häckel, "Generelle Morphologie der Organismen", 1866)
"Isolated facts and experiments have in themselves no value, however great their number may be. They only become valuable in a theoretical or practical point of view when they make us acquainted with the law of a series of uniformly recurring phenomena, or, it may be, only give a negative result showing an incompleteness in our knowledge of such a law, till then held to be perfect." (Hermann von Helmholtz, "The Aim and Progress of Physical Science", 1869)
"The aim of natural science is to obtain connections among phenomena. Theories, however, are like withered leaves, which drop off after having enabled the organism of science to breathe for a time." (Ernst Mach, "Die Geschichte und die Wurzel des Satzes von der Erhaltung der Arbeit", 1871)
"The mind of man may be compared to a musical instrument with a certain range of notes, beyond which in both directions we have an infinitude of silence. The phenomena of matter and force lie within our intellectual range, and as far as they reach we will at all hazards push our inquiries. But behind, and above, and around all, the real mystery of this universe [Who made it all?] lies unsolved, and, as far as we are concerned, is incapable of solution." (John Tyndall, "Fragments of Science for Unscientific People", 1871)
"So intimate is the union between Mathematics and Physics that probably by far the larger part of the accessions to our mathematical knowledge have been obtained by the efforts of mathematicians to solve the problems set to them by experiment, and to create for each successive class phenomena a new calculus or a new geometry, as the case might be, which might prove not wholly inadequate to the subtlety of nature. Sometimes the mathematician has been before the physicist, and it has happened that when some great and new question has occurred to the experimentalist or the observer, he has found in the armory of the mathematician the weapons which he needed ready made to his hand. But much oftener, the questions proposed by the physicist have transcended the utmost powers of the mathematics of the time, and a fresh mathematical creation has been needed to supply the logical instrument requisite to interpret the new enigma." (Henry J S Smith, Nature, Volume 8, 1873)
"Hence, even in the domain of natural science the aid of the experimental method becomes indispensable whenever the problem set is the analysis of transient and impermanent phenomena, and not merely the observation of persistent and relatively constant objects." (Wilhelm Wundt, "Principles of Physiological Psychology", 1874)
"It is the prerogative of Intellect to discover what is uniform and unchanging in the phenomena around us." (William S Jevons, "The Principles of Science: A Treatise on Logic and Scientific Method", 1874)
"When we merely note and record the phenomena which occur around us in the ordinary course of nature we are said to observe. When we change the course of nature by the intervention of our will and muscular powers, and thus produce unusual combinations and conditions of phenomena, we are said to experiment. […] an experiment differs from a mere observation in the fact that we more or less influence the character of the events which we observe." (William S Jevons, "The Principles of Science: A Treatise on Logic and Scientific Method", 1874)
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